Detalhe da pesquisa
1.
The Logic of the 26S Proteasome.
Cell
; 169(5): 792-806, 2017 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28525752
2.
Molecular mechanism for activation of the 26S proteasome by ZFAND5.
Mol Cell
; 83(16): 2959-2975.e7, 2023 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37595557
3.
Immuno- and constitutive proteasomes do not differ in their abilities to degrade ubiquitinated proteins.
Cell
; 152(5): 1184-94, 2013 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23452861
4.
Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis.
Cell
; 153(5): 1012-24, 2013 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23706739
5.
Cancer vulnerabilities unveiled by genomic loss.
Cell
; 150(4): 842-54, 2012 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22901813
6.
Maximum entropy determination of mammalian proteome dynamics.
Proc Natl Acad Sci U S A
; 121(18): e2313107121, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38652742
7.
ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycle.
Cell
; 144(4): 526-38, 2011 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21335235
8.
A conserved F box regulatory complex controls proteasome activity in Drosophila.
Cell
; 145(3): 371-82, 2011 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-21529711
9.
Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival.
Cell
; 142(4): 531-43, 2010 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20723755
10.
26S proteasomes become stably activated upon heat shock when ubiquitination and protein degradation increase.
Proc Natl Acad Sci U S A
; 119(25): e2122482119, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35704754
11.
Getting to first base in proteasome assembly.
Cell
; 138(1): 25-8, 2009 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19596233
12.
Mammalian Ddi2 is a shuttling factor containing a retroviral protease domain that influences binding of ubiquitylated proteins and proteasomal degradation.
J Biol Chem
; 298(5): 101875, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35358511
13.
Raising cGMP restores proteasome function and myelination in mice with a proteotoxic neuropathy.
Brain
; 145(1): 168-178, 2022 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34382059
14.
Blocking Cancer Growth with Less POMP or Proteasomes.
Mol Cell
; 59(2): 143-5, 2015 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26186288
15.
Multiple myeloma cells are exceptionally sensitive to heat shock, which overwhelms their proteostasis network and induces apoptosis.
Proc Natl Acad Sci U S A
; 117(35): 21588-21597, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32817432
16.
Proteins containing ubiquitin-like (Ubl) domains not only bind to 26S proteasomes but also induce their activation.
Proc Natl Acad Sci U S A
; 117(9): 4664-4674, 2020 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32071216
17.
cGMP via PKG activates 26S proteasomes and enhances degradation of proteins, including ones that cause neurodegenerative diseases.
Proc Natl Acad Sci U S A
; 117(25): 14220-14230, 2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32513741
18.
An allosteric switch regulates Mycobacterium tuberculosis ClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR.
Proc Natl Acad Sci U S A
; 117(11): 5895-5906, 2020 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32123115
19.
26S Proteasomes are rapidly activated by diverse hormones and physiological states that raise cAMP and cause Rpn6 phosphorylation.
Proc Natl Acad Sci U S A
; 116(10): 4228-4237, 2019 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30782827
20.
SIP/CacyBP promotes autophagy by regulating levels of BRUCE/Apollon, which stimulates LC3-I degradation.
Proc Natl Acad Sci U S A
; 116(27): 13404-13413, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31213539